
Rejuran in Korea
Known in the U.S. as the salmon DNA skin booster. See what it can do for texture, fine lines, and glow.
En un coup d’œil
- Approach
- PN micro-injections
- Treatment time
- About 1 hour
- Downtime
- Small bumps, 1–2 days
- Typical plan
- Often a course of 3
- Results appear
- Gradually, over weeks
- Results may last
- Several months
- Rejuran is a Korean brand of polynucleotide (PN) injections made from purified salmon DNA — often called a skin booster.
- It is used to improve skin quality: texture, fine lines, resilience, and a healthy-looking glow.
- Change builds gradually over a course of treatments, usually a few sessions spaced weeks apart.
- It does not add volume or lift sagging skin. A clinician should assess your goals.
Great skincare, still tired skin?

- Purified salmon DNA (PN)
- Numbing cream is standard
- Not a filler — no added volume
- Temporary bumps and redness
Board-certified specialists
Korean dermatologists & plastic surgeons
Clear treatment plans
Know what’s included before you book
English support
Interpretation arranged when needed
Rough texture, fine lines, or a dull, dehydrated look can make you curious about skin boosters.
With time, sun, and stress, skin renews itself more slowly. Skincare supports the surface, but it cannot place ingredients into the deeper skin layer the way an injection can.
Not every concern is a skin-quality concern. Deeper lines, sagging, and volume loss call for different approaches.
Texture and glow are your goal
If dullness, fine lines, or uneven texture bother you most, a PN skin booster may be worth discussing. Discuss skin boosters.
Your skin looks thin or sensitive
Rejuran is often considered for fragile-looking or easily irritated skin. Your clinician should check your skin condition first. Ask about suitability.
Sagging or hollowness is the main issue
Rejuran improves skin quality, not structure. Lifting or volume treatments may be a better fit. Consider other options.
These changes can overlap. A specialist’s assessment helps match what you see with the right options.
Understand your skin better
Start with a free online AI skin analysis to explore your skin type and put your concerns into words. Bring what you learn to a consultation for a more focused conversation about your goals.
Free AI skin analysisSkin quality, laxity, and volume are different concerns. Start with an assessment.
Is skin quality your priority?
The aim is healthier-looking, more resilient skin — a natural change, not a new face.
Concerns worth discussing
- Rough or uneven skin texture
- Fine lines and early signs of aging
- Dull, dehydrated-looking skin
- A preference for natural, gradual change
Tell your clinician about
- Your medical history, medications, and previous procedures
- Fish or salmon allergies, pregnancy, or an active skin infection
Why people choose it
- Improves skin quality without changing your features
- Widely used in Korea for over a decade
- A favorite for the K-beauty “glass skin” look
- Short downtime; small bumps usually fade in a day or two
Good to know
- Results build over a course of sessions, not one visit
- Injections can sting; numbing cream helps
The right plan depends on your skin, your goals, and how your skin responds.
Boost, hydrate, or fill?
Start with what you want to improve — skin quality, hydration, texture, or volume. Each treatment plays a different role.

Where does skincare fit? Rejuran also has a topical skincare line. Creams and serums can support hydration, but they do not work like the injected treatment, which places PN directly into the skin.
| Option | Often considered for | Approach | Recovery |
|---|---|---|---|
| Rejuran (PN) | Skin quality: texture, fine lines, glow, resilience | Polynucleotide (PN) micro-injections | Small bumps for 1–2 days; bruising possible |
| HA skin boosters | Hydration and a dewy-looking finish | Hyaluronic acid micro-injections | Small bumps or mild swelling |
| RF microneedling | Texture, acne scars, fine lines, and laxity | Radiofrequency through needles | Visible redness or recovery may occur |
| Fillers | Volume loss and contour | Gel injected to restore volume | Varies by product and area |
Supporting your skin’s own renewal.
Rejuran contains polynucleotides (PN) — purified DNA fragments derived from salmon. Placed into the skin through fine micro-injections, PN is thought to support the skin’s natural repair processes, including collagen production.
Change develops gradually over a course of treatments. Rejuran improves skin quality; it does not add volume or lift sagging skin.
PN skin booster vs. Rejuran: what’s the difference?
PN is the ingredient
Polynucleotide is the active ingredient. Several companies make PN skin boosters.
Rejuran is the brand
Rejuran is PharmaResearch’s PN product line from Korea, with versions for different areas and concerns.
Injection vs. skincare
Rejuran injections are a clinic treatment. Rejuran-branded creams are topical skincare — a different product.
The best treatment is the one that matches your concern.
Healthier-looking skin, same face.
The aim is healthier-looking skin with a natural finish. How much changes depends on your skin and how it responds.

Smoother-looking texture
Skin may feel smoother and look more even over the course of treatment.
Softer-looking fine lines
Fine, crepey lines may look softer as skin quality improves.
A healthy, rested glow
Many people notice skin that looks more hydrated and luminous — the “glass skin” look.
Expect a natural, gradual improvement in skin quality. Rejuran does not replace lost volume or lift sagging skin.
A glow that builds, session by session.
Right after
Small raised bumps at injection points are expected and usually settle within 1–2 days. Redness or minor bruising can occur.
After a few weeks
Skin quality often improves gradually, with more change after each session in the course.
Several months
Results can last several months. Many people plan maintenance sessions after reassessment.
See your texture change in 3D.
At equipped partner clinics, 3D AI skin analysis records detailed images and measurements. Your specialist combines these with an in-person assessment. This is separate from the free online skin analysis.
Standardized 3D capture
Repeat imaging under similar angles, lighting, and distance for useful comparisons.
AI skin measurements
Detailed images and measurements of your current skin condition.
A baseline for your follow-up
Compare your skin at your next visit under similar imaging conditions.
A Rejuran visit, start to finish
Allow time for the full appointment as well as the treatment itself. Share your travel dates and any other procedures you are planning.

Before treatment · Consultation & planning
Review your skin, goals, and medical history. At clinics offering 3D analysis, review your baseline together. Agree on the plan and quote before proceeding.
About 1 hour · Treatment
Numbing cream is applied first. You may feel stinging or pressure during the micro-injections. Tell your clinician if discomfort is significant.
Same day · Aftercare & next steps
Get recovery guidance, symptoms to watch for, and any recommended review timing. Keep your treatment records and the clinic’s contact details.
What it feels like
- Numbing cream is applied 20–30 minutes before treatment
- Fine needles place PN evenly across the treatment area
- Injections may sting, especially where skin is thinner
- Speak up if you experience significant discomfort
Allow time for your full visit
Assessment · Before treatment
Goals, anatomy, and medical history
Treatment · About 1 hour
Time varies by area and plan
Aftercare · Before you leave
Recovery guidance and review timing
Share your travel dates and other planned procedures. Small bumps usually settle within 1–2 days — plan photos and events accordingly.
Tiny bumps, short-lived.
Small bumps, redness, and mild swelling at injection points are common and usually settle within a day or two. Minor bruising can occur and may take longer to fade.
As with any injection, infection, prolonged swelling, or allergic reactions are possible. Tell your clinic about fish or other allergies, and discuss these risks before treatment.
Leave with clear aftercare guidance
Protect your skin
Ask your clinician about makeup, sun exposure, saunas, and exercise after treatment.
Know what to watch for
Ask which symptoms are expected and when to contact the clinic.
Keep a contact plan
Take your treatment records and the clinic’s contact details with you.
What should I share before treatment?
Share your medical history, medications, implants, and previous cosmetic procedures with your clinic. Their medical team will check whether the treatment suits you.
Same vial, different technique.

You can compare skin boosters and still be unsure which change a treatment would make for you. That is where a personalized assessment helps: connecting what you see in the mirror with the options that fit.
The same product does not mean the same treatment experience. Injection technique, depth, and dosage vary between clinicians, and your skin condition and goals shape the plan.
Board-certified specialists in Korea
Lulu@ helps you connect with experienced, Korean board-certified dermatologists and plastic surgeons. Discuss what may be contributing to the changes you notice, compare options, and understand the result each approach could offer.
3D AI skin analysis for personalized planning
At equipped partner clinics, a 3D AI skin analysis device records detailed images and measurements of your current skin condition. Your specialist combines this with an in-person assessment and your goals to develop a personalized plan.
Support to understand your options
Explore clinics with English-language support through Lulu@. Interpretation support can also be arranged when needed, helping you explain your concerns and ask questions with greater confidence.
What matters when choosing a clinic?
Look beyond the product name or the number of injections. Ask who assesses your skin, who performs the procedure, and how the plan accounts for your goals.
Understand the proposed areas, realistic change, comfort measures, risks, full cost, and follow-up before deciding.
What to know before getting aesthetic treatments in KoreaWhat to ask before you book Rejuran.
A few direct questions during consultation tell you a lot about the kind of care you are choosing.
What to check before choosing a clinic
- How experienced is the clinician with Rejuran?
- Can you confirm the product is genuine Rejuran?
- How many sessions and which areas are included?
- Do they tailor the treatment to your face?
- Do they explain side effects and recovery up front?
- Is follow-up consultation available after treatment?
A consultation should leave you with clear answers.
What is contributing to the change? Which options fit your goals? What improvement is realistic? A personalized plan brings those answers together with the treatment area, approach, risks, and cost.
Book a consultationChoose a clinic on Lulu@, then select Book Consultation on its page.
Still curious about Rejuran?
Is Rejuran really made from salmon?
Yes. Rejuran’s PN is a highly purified ingredient derived from salmon DNA. Tell your clinic if you have a fish or seafood allergy.
Is Rejuran painful?
Micro-injections can sting, especially where skin is thinner. Numbing cream is standard. Discuss comfort options and tell your clinician if discomfort is significant.
Is Rejuran the same as a filler?
No. Rejuran is a skin booster. It aims to improve skin quality, not add volume or reshape your features.
How many sessions will I need?
Many clinics suggest a course of about three sessions a few weeks apart, followed by maintenance. Your clinician will recommend a plan based on your skin.
Check your skin quality first.
You do not need to arrive with a treatment decision. Start by understanding your concerns, or talk with a specialist about the changes you would like to see.
Understand your skin better
Use the free online AI skin analysis to explore your skin type and organize what you want to discuss.
Make your next step personal
Discuss your concerns, suitable options, and realistic results with a Korean board-certified specialist.
Choose a clinic on Lulu@, then select Book Consultation on its page.
Keep exploring
More guides to help you plan treatment in Korea.
Ultherapy in Korea
Explore focused ultrasound for brow, under-chin, and neck lifting.
Ultherapy in KoreaRF microneedling in Korea
When texture and acne scars are part of the concern.
RF microneedling in KoreaGetting aesthetic treatments in Korea
What international patients should know beyond the price.
Getting aesthetic treatments in KoreaPoursuivre la découverte
Written by the Lulu@ editorial team. Content preview · Medical review pending. General education, not an individual diagnosis or treatment recommendation. A qualified clinician should assess suitability. Rejuran® is a trademark of PharmaResearch Co., Ltd.

